Sinopsis
Laboratory medicine, more commonly referred to as clinical pathology (or bioanalytical pathology), is a distinct specialty that overlaps other medicine specialties such as internal medicine and oncology in the area of diagnostics. In contrast to internists, clinical pathologists practice a systems-based rather than problem-based approach when interpreting hematologic and biochemical results. However, in addition to recognizing disease-associated changes, two other phenomena contribute to test interpretation: how test results are generated and how “normal” is defined. Artifacts due to sample preparation, sample condition, or disease processes need to be identified and distinguished from true disease-associated changes. Similarly, test interpretation is always performed in context—the context of “health.” The accuracy of the test methodology and the reference intervals generated from the methodology are essential to the ability to diagnose disease. This chapter provides information on hematologic and biochemical test methodologies and validation, and discusses the basic knowledge needed for generating and/or using reference intervals. The remainder of the book addresses test interpretation using a systems-based approach.
Content
- General Laboratory Medicine
- Equine Hematology
- Immunohematology and Hemostasis
- The Liver
- Laboratory Evaluation of the Equine Renal System
- Acid-Base and Electrolytes
- Proteins
- Laboratory Assessment of Lipid and Glucose Metabolism
- Skeletal Muscle
- Endocrine Evaluation
- Fluid Analysis
- Cytology of the Lower Respiratory Tract
- Cerebrospinal Fluid
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