Download PDF Infectious Disease: Pathogenesis, Prevention, and Case Studies by N. Shetty
Sinopsis
Microbes and their habitats have held a peculiar fascination for mankind ever since Antony van Leeuwenhoek (1632–1723) recorded some of the most important discoveries in the history of biology. Once Leeuwenhoek succeeded in creating the simple microscope, he described bacteria, free-living and parasitic creatures, sperm cells, blood cells, microscopic nematodes and much more. His publications opened up an entire world of microscopic life for scientific study. Microbes continue to excite intense research because of their virulence; their ability to cause tissue damage and death. They have been responsible for the great plagues and epidemics and have often changed the course of human history. The HIV pandemic has emerged as the single most defining occurrence in the history of infectious diseases of the late 20th and early 21st centuries. Microbes continue to baffle human ingenuity; they defy attempts at control by chemotherapeutic agents, vaccines, and the human immune system. The threat of a future pestilence is never far away. In order to study the microbial etiology of infectious disease, an understanding of the basic principles of microbiology and their interaction with the human host are essential. There are four basic groups of microbes:
- Bacteria
- Viruses
- Fungi: yeasts and molds
- Protozoa.
Content
- GENERAL PRINCIPLES OF INFECTIOUS DISEASES
- Microbial etiology of disease
- Structure and function of microbes
- Host defence versus microbial pathogenesis and the mechanisms of microbial escape
- Diagnosis of microbial infection
- General principles of antimicrobial chemotherapy
- Basic concepts of the epidemiology of infectious diseases
- A SYSTEMS BASED APPROACH TO INFECTIOUS DISEASES
- Infections of the skin, soft tissue, bone, and joint
- Gastroenteritis
- Cardiac and respiratory tract infections
- Infections of the central nervous system
- Infections of the genitourinary system
- INFECTIONS IN SPECIAL GROUPS
- Obstetric, congenital and neonatal infections
- Infections in the immunocompromised host
- Healthcare associated infections
- The fever and rash conundrum: rashes of childhood
- INFECTIONS OF GLOBAL IMPACT
- Tuberculosis
- Malaria
- Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)
- Viral hepatitis
- Influenza
- Infections in the returning traveler
- EMERGING AND RESURGENT INFECTIONS
- Viral hemorrhagic fevers
- Emerging infections I (human monkeypox, hantaviruses, Nipah virus, Japanese encephalitis, chikungunya
- Emerging infections II (West Nile virus, dengue, severe acute respiratory syndrome-associated coronavirus)
- Diphtheria
- Agents of bioterrorism
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